References – 2021

Rodrigues ES, Romagnoli AC, Santos FLS, Cutter TB, Catelli LF, Cédric V, Peyrard T, Covas DT, de Castilho LM, Kashima S. Frequency and characterization of RHD variant alleles in a population of blood donors from southeastern Brazil: Comparison with other populations. Transfus Apher Sci. 2021 Apr 8:103135.

Pereira-Martins DA, Weinhäuser I, Coelho-Silva JL, França-Neto PL, Almeida LY, Bianco TM, Silva CL, França RF, Traina F, Rego EM, Schuringa JJ, Lucena-Araujo AR. MLL5 improves ATRA driven differentiation and promotes xenotransplant engraftment in acute promyelocytic leukemia model. Cell Death Dis. 2021 Apr 6;12(4):371.

de Lima SCG, Fantacini DMC, Batista LC, Silveira RM, Furtado IP, Rossetti R, Brand H, Covas DT, de Souza LEB. Strategies to Enhance the Therapeutic Efficacy, Applicability, and Safety of Genetically Engineered Immune Cells. Crit Rev Immunol. 2021;41(1):41-67.

Barros II, Leão V, Santis JO, Rosa RCA, Brotto DB, Storti CB, Siena ÁDD, Molfetta GA, Silva WA Jr. Non-Syndromic Intellectual Disability and Its Pathways: A Long Noncoding RNA Perspective. Noncoding RNA. 2021 Mar 11;7(1):22.

Amaku M, Covas DT, Coutinho FAB, Azevedo RS, Massad E. Modelling the impact of contact tracing of symptomatic individuals on the COVID-19 epidemic. Clinics (Sao Paulo). 2021 Mar 26;76:e2639.

De Santis GC, Mendrone A, Langhi D Jr, Covas DT, Fabron A Jr, Cortez AJP, Dinardo CL, Ubiali EMA, Marques JFC Jr, Bordin JO, Rugani MA. Suggested guidelines for convalescent plasma therapy for the treatment of COVID-19. Hematol Transfus Cell Ther. 2021 Mar 20.

Garibaldi PMM, Ferreira NN, Moraes GR, Moura JC, Espósito DLA, Volpe GJ, Calado RT, Fonseca BAL, Borges MC. Efficacy of COVID-19 outbreak management in a skilled nursing facility based on serial testing for early detection and control. Braz J Infect Dis. 2021 Mar 23;25(2):101570.

Aich A, Lamarre Y, Sacomani DP, Kashima S, Covas DT, de la Torre LG. Microfluidics in Sickle Cell Disease Research: State of the Art and a Perspective Beyond the Flow Problem. Front Mol Biosci. 2021 Mar 8;7:558982.

Obatoclax reduces cell viability of acute myeloid leukemia cell lines independently of their sensitivity to venetoclax. Lima K, Vicari HP, Carlos JAEG, da Silva JCL, Figueiredo-Pontes LL, Rego EM, Machado-Neto JA. Hematol Transfus Cell Ther. 2021 Mar 13:S2531-1379(21)00026-2.

Mazzarella R, Bastos NM, Bridi A, Del Collado M, Andrade GM, Pinzon J, Prado CM, Silva LA, Meirelles FV, Pugliesi G, Perecin F, da Silveira JC. Changes in Oviductal Cells and Small Extracellular Vesicles miRNAs in Pregnant Cows. Front Vet Sci. 2021 Mar 4;8:639752.

Da Luz CM, Da Broi MG, Plaça JR, Silva WA Jr, Meola J, Navarro PA. Altered transcriptome in cumulus cells of infertile women with advanced endometriosis with and without endometrioma. Reprod Biomed Online. 2021 Feb 8:S1472-6483(21)00058-4.

Dos Santos Bezerra R, Bub CB, Peronni KC, de Figiueiredo Barros BD, da Costa Lira SM, Kutner JM, Covas DT, Kashima S, Slavov SN. Virome comparison of deferred blood donations obtained from different geographic regions in the Sao Paulo State, Brazil. Transfus Apher Sci. 2021 Mar 10:103106.

Lima-Júnior JR, Arruda LCM, Gonçalves MS, Dias JBE, Moraes DA, Covas DT, Simões BP, Oliveira MC, Malmegrim KCR. Autologous hematopoietic stem cell transplantation restores the suppressive capacity of regulatory B cells in systemic sclerosis patients. Rheumatology (Oxford). 2021 Mar 16:keab257.

Fonseca AS, Ramão A, Bürger MC, de Souza JES, Zanette DL, de Molfetta GA, de Araújo LF, de Barros E Lima Bueno R, Aguiar GM, Plaça JR, Alves CP, Dos Santos ARD, Vidal DO, Silva GEB, Panepucci RA, Peria FM, Feres O, da Rocha JJR, Zago MA, Silva WA Jr. ETV4 plays a role on the primary events during the adenoma-adenocarcinoma progression in colorectal cancer. BMC Cancer. 2021 Mar 1;21(1):207.

Ferreira FR, Cupido A, Catalin B, Silva WA Jr, Kirchhoff F, Del-Bel EA, Guimarães FS. Astrocyte Intracellular Ca2+and TrkB Signaling in the Hippocampus Could Be Involved in the Beneficial Behavioral Effects of Antidepressant Treatment. Neurotox Res. 2021 Feb 22.

Gutierrez-Rodrigues F, Alves-Paiva RM, Scatena NF, Martinez EZ, Scheucher PS, Calado RT. Association between leukocyte telomere length and sex by quantile regression analysis. Hematol Transfus Cell Ther. 2021 Feb 6:S2531-1379(21)00005-5.

Maciel NIG, Filiú-Braga LDC, Neves FAR, Rego EM, Lucena-Araujo AR, Saldanha-Araujo F. Low expression of ZHX1 and ZHX2 impacts on the prognosis of chronic lymphocytic leukemia. Biomark Res. 2021 Feb 4;9(1):10.

Mastellos DC, Skendros P, Calado RT, Risitano AM, Lambris JD. Efficacy matters: broadening complement inhibition in COVID-19. Lancet Rheumatol. 2021 Feb;3(2):e95.

Souza RB, Gyuricza IG, Cassiano LL, Farinha-Arcieri LE, Alvim Liberatore AM, Schuindt do Carmo S, Caldeira W, Cruz MV, Ribeiro AF, Tedesco RC, Reinhardt DP, Smith R, Jun Koh IH, Pereira LV. The mgΔlpn mouse model for Marfan syndrome recapitulates the ocular phenotypes of the disease. Exp Eye Res. 2021 Mar;204:108461.

Vilela CAP, Messias A, Calado RT, Siqueira RC, Silva MJL, Covas DT, Paula JS. Retinal function after intravitreal injection of autologous bone marrow-derived mesenchymal stromal cells in advanced glaucoma. Doc Ophthalmol. 2021 Jan 19.

Coelho-Silva JL, Silveira DRA, Pereira-Martins DA, Rojas CAO, Lucena-Araujo AR, Rego EM, Machado-Neto JA, Bendit I, Rocha V, Traina F .Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome. Sci Rep. 2021 Jan 18;11(1):1675.

Scopim-Ribeiro R, Machado-Neto JA, Eide CA, Coelho-Silva JL, Fenerich BA, Fernandes JC, Scheucher PS, Savage Stevens SL, de Melo Campos P, Olalla Saad ST, de Carvalho Palma L, de Figueiredo-Pontes LL, Simões BP, Rego EM, Tognon CE, Druker BJ, Traina F. NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia. Invest New Drugs. 2021 Jan 6.

Rossetti R, Rós FA, Souza LEB, Maçonetto JM, Costa PNMD, Ferreira FU, Borges JS, Carvalho JV, Morotti NP, Kashima S, Covas DT .Hypoxia-cultured mouse mesenchymal stromal cells from bone marrow and compact bone display different phenotypic traits. Exp Cell Res. 2021 Feb 1;399(1):112434.

Rocha JLM, de Oliveira WCF, Noronha NC, Dos Santos NCD, Covas DT, Picanço-Castro V, Swiech K, Malmegrim KCR. Mesenchymal Stromal Cells in Viral Infections: Implications for COVID-19. Stem Cell Rev Rep. 2021 Feb;17(1):71-93.

Valença IN, Rós FA, Zucherato VS, Silva-Pinto AC, Covas DT, Kashima S, Slavov SN. Comparative metavirome analysis in polytransfused patients. Braz J Med Biol Res.2021 Oct 18;54(12):e11610.

Slavov SN, Patané JSL, Bezerra RDS, Giovanetti M, Fonseca V, Martins AJ,Viala VL,Rodrigues ES,Santos EV, Barros CRS, Marqueze EC,Santos B, Aburjaile F, Neto RM, Moretti DB, Haddad R, Calado RT, Kitajima JP, Freitas E, Schlesinger D, Junior de Alcantara LC, Elias MC, Sampaio SC, Kashima S, Covas DT. Genomic monitoring unveil the early detection of the SARS-CoV-2 B.1.351 (beta) variant (20H/501Y.V2) in Brazil. Journal of Medical Virology, 2021, 93(12), pp. 6782–6787. 

Slavov SN, Giovanetti M, Dos Santos Bezerra R, Fonseca V, Santos EV, Rodrigues ES, Adelino T,Xavier J, Borges JS, Evaristo M, Lima MT, De Carvalho Pereira G,Yamamoto AY, Clé DV, Calado RT, Covas DT,Alcantara LCJ, Kashima S. Molecular surveillance of the on-going SARS-COV-2 epidemic in Ribeirao Preto City, Brazil. Infect Genet Evol. 2021 Sep;93:104976 

De Santis GC, Ubiali EMA, Zanelli APRD, Mendrone Junior A, Feitoza A, Kutner JM, Orellana MD, Rizzo SRCP, Covas DT, Langhi Junior DM. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VI: Accreditation process. Hematol Transfus Cell Ther. 2021 Nov;43 Suppl 2:S42-S45.

De Santis GC, Langhi Junior DM, Feitoza A, Mendrone Junior A, Kutner JM, Covas DT, Couto SCF, Guerino-Cunha RL, Orellana MD, Rizzo SRCP. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. V: Manufacture and quality control. Hematol Transfus Cell Ther. 2021 Nov;43 Suppl 2:S35-S41. 

Valença IN, Bezerra RDS, De Oliveira LCO, Covas DT, Kashima S, Slavov SN. Deep viral metagenomics in patients with haemophilia receiving plasma-derived coagulation factor concentrates. Haemophilia. 2021 Sep;27(5):e645-e648.Epub 2021 Jul 27. 

Langhi Junior DM, Maiolino A, Chiattone CS, De Souza CA, Covas DT, Costa FF, Guerino-Cunha RL, Pasquini R. The Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular seeks the implementation of, and access to, the CAR-T cell treatment in Brazil.Hematol Transfus Cell Ther. 2021 Nov;43 Suppl 2:S1-S2. Epub 2021 Jul 22. 

De Almeida LY, Pereira-Martins Diego A, Weinhäuser I, Ortiz C, Cândido Larrisa A, Lange AP, De Abreu NF, Mendonza SES, de Deus Wagatsuma VM, Do Nascimento MC, Paiva HH, Alves-Paiva RM, Bonaldo CCOM, Nascimento DC, Alves-Filho JC, Scheucher PS, Lima ASG, Schuringa JJ, Ammantuna E, Ottone T, Nogueira NI, Araujo CL, Rego EM. The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells. Front Oncol. 2021 Sep 28;11:686445.

Mendes FR, Da Silva WF, da Costa Bandeira de Melo R, Silveira DRA, Velloso EDRP, Rocha V, Rego EM. Predictive factors associated with induction-related death in acute myeloid leukemia in a resource-constrained setting. Ann Hematol. 2021 Oct 21. 

Picanço-Castro V, Bonamino MH, Ramos RN, Guerino-Cunha RL, Oliveira TGM, Rego EM. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. VIII: CAR-T cells: preclinical development – Safety and efficacy evaluation. Hematol Transfus Cell Ther. 2021 Nov;43 Suppl 2:S54-S63. 

Da Silveira JC, Andrade GM, Simas RC, Martins-Júnior HA, Eberlin MN, Smith LC, Perecin F, Meirelles FV. Lipid profile of extracellular vesicles and their relationship with bovine oocyte developmental competence: New players in intra follicular cell communication.Theriogenology. 2021 Oct 15;174:1-8. 

Ribeiro VB, Pedroso DCC, Kogure GS, Lopes IP, Santana BA, De Souza HCD, Ferriani RA, Calado RT, Furtado CLM, Dos Reis RM. Short-Term Aerobic Exercise Did Not Change Telomere Length While It Reduced Testosterone Levels and Obesity Indexes in PCOS: A Randomized Controlled Clinical Trial Study.Int J Environ Res Public Health. 2021 Oct 27;18(21):11274. 

De Oliveira BCD, Shiburah ME, Paiva SC, Vieira MR, Morea EGO, da Silva MS, Alves CS, Segatto M, Gutierrez-Rodrigues F, Borges JC, Calado RT, Cano MIN.Possible Involvement of Hsp90 in the Regulation of Telomere Length and Telomerase Activity During the Leishmania amazonensis Developmental Cycle and Population Proliferation. Front Cell Dev Biol. 2021 Oct 28;9:713415. 

Debureaux PE, Kulasekararaj AG, Cacace F, Silva BGP, Calado RT, Barone F, Sicre de Fontbrune F, Prata PH, Soret J, Sica M, Notaro R, Scheinberg P, Mallikarjuna V, Gandhi S, Large J, Risitano AM, Peffault de Latour R, Frieri C. Categorizing hematological response to eculizumab in paroxysmal nocturnal hemoglobinuria: a multicenter real-life study. Bone Marrow Transplant. 2021 Oct;56(10):2600-2602. 

Serpeloni JM, Lima Neto QA, Lucio LC, Ramão A, Carvalho de Oliveira J, Gradia DF, Malheiros D, Ferrasa A, Marchi R, Figueiredo DLA, Silva WA Jr, Ribeiro EMSF, Cólus IMS, Cavalli LR.Genome interaction of the virus and the host genes and non-coding RNAs in SARS-CoV-2 infection. Immunobiology. 2021 Sep;226(5):152130. Epub 2021 Aug 17. 

Silveira MLC, Tamashiro E, Santos ARD, Martins RB, Faria FM, Silva LECM, Torrieri R, de C Ruy P, Silva WA Jr, Arruda E, Anselmo-Lima WT, Valera FCP.miRNA-205-5p can be related to T2-polarity in Chronic Rhinosinusitis with Nasal Polyps. Rhinology. 2021 Oct 5.

Dinarte VRP, Silva WA Jr, Baccarin ARD, Tamashiro E, Valera FC, Anselmo-Lima WT. Association of interleukin 22 receptor subunit alpha 1 gene polymorphisms with chronic rhinosinusitis. Braz J Otorhinolaryngol. 2021 Sep-Oct;87(5):505-511. 

Arthur RA, Dos Santos Bezerra R, Ximenez JPB, Merlin BL, de Andrade Morraye R, Neto JV, Fava NMN, Figueiredo DLA, de Biagi CAO Jr; Summer Course 2020 group, Montibeller MJ, Guimarães JB, Alves EG, Schreiner M, da Costa TS, da Silva CFL, Malheiros JM, da Silva LHB, Ribas GT, Achallma DO, Braga CM, Andrade KFA, do Carmo Alves Martins V, Dos Santos GVN, Granatto CF, Terin UC, Sanches IH, Ramos DE, Garay-Malpartida HM, de Souza GMP, Slavov SN, Silva WA Jr.Microbiome and oral squamous cell carcinoma: a possible interplay on iron metabolism and its impact on tumor microenvironment. Braz J Microbiol. 2021 Sep;52(3):1287-1302. 

Moreira MLM, de Araújo IM, de Molfetta GA, Silva WA Jr, de Paula FJA. Repetitive stress fracture: a warning sign of genetic susceptibility to fracture? A case report of a heterozygous variant in SERPINF1. Arch Endocrinol Metab. 2021 Nov 3;65(4):500-504.

De Souza AF, Bressan FF, Pieri NCG, Botigelli RC, Revay T, Haddad SK, Covas DT, Ramos ES, King WA, Meirelles FV. Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients. Cells. 2021 Nov 10(11): 3099. https://doi.org/10.3390/cells10113099

Vicari HP, Coelho-Silva JL, Pereira-Martins DA, Lucena-Araujo AR, Lima K, Lipreri da Silva JC, Scheucher PS, Koury LC, De Melo RA, Bittencourt R, Pagnano K, Nunes E, Fagundes EM, Kerbauy F, de Figueiredo-Pontes LL, Costa-Lotufo LV, Rego EM, Traina F, Machado-Neto JA. STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells. Invest New Drugs. 2021 Nov 27. https://doi.org/10.1007/s10637-021-01197-0

De Souza RB, Kawahara EI, Farinha-Arcieri LE, Gyuricza IG, Neofiti-Papi B, Miranda-Rodrigues M, Teixeira MBCG, Fernandes GR, Lemes RB, Reinhardt DP, Gouveia CH, Pereira LV. Hyperkyphosis is not dependent on bone mass and quality in the mouse model of Marfan syndrome. Bone. 2021 Nov;152:116073 https://doi.org/10.1016/j.bone.2021.116073

Viana AR, Davidson CB, Salles B, DE Almeida LY, Krause A, Bizzi CA, Rego EM, Fontanari Krause LM, Mortari SR. Activity of Free and Liposomal Antimony Trioxide in the Acute Promyelocytic Leukemia Cell Line NB4. Anticancer Res. 2021 Dec;41(12):6061-6065. https://doi.org/10.21873/anticanres.15425

Medina-Pestana J, Covas DT, Viana LA, Dreige YC, Nakamura MR, Lucena EF, Requião-Moura LR, Fortaleza CMCB, Foresto RD, Tedesco-Silva H, Cristelli MP. Inactivated Whole-virus Vaccine Triggers Low Response Against SARS-CoV-2 Infection Among Renal Transplant Patients: Prospective Phase 4 Study Results. Transplantation. 2021 Dec 7. https://doi.org/10.1097/TP.0000000000004036

Lesbon JCC, Poleti MD, de Mattos Oliveira EC, Patané JSL, Covas DT, Calado RT, et al. Nucleocapsid (N) Gene Mutations of SARS-CoV-2 Can Affect Real-Time RT-PCR Diagnostic and Impact False-Negative Results. Viruses. 2021 Dec 10;13(12):2474.

Medina-Pestana J, Teixeira CM, Cristelli MP, Amiratti AL, Manfredi SR, Tedesco-Silva H, Covas DT. Clinical impact, reactogenicity and immunogenicity after the first CoronaVac dose in dialysis patients: a Phase IV prospective study. Clin Kidney J. 2021 Dec;14(12):2612-2615.

De Azevedo JTC, Costa TCM, Lima KC, Maciel TT, De Santis GC, Covas DT, et al. Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients. Front Immunol. 2021 Dec 9;(12):774442.